A Unique Ring-Expanded Acyclic Nucleoside Analogue That Inhibits Both Adenosine Deaminase and Guanine Deaminase (Guanase):
Synthesis and Biochemical Screening of4,8-Diamino-6H-1-hydroxyethoxymethyl-6-iminoimidazo[4,5-e][1,3]diazepine
Wang, Lijuan; Hosmane, Ramachandra, S.
Laboratory for Drug Design and Synthesis, Department of Chemistry & Biochemistry,
University of Maryland, Baltimore County, 1000 Hilltop
Circle, Baltimore, Maryland 21250, USA. Phone: (410)-455-2520 Fax: (410)-455-1148 E-Mail:
hosmane@research.umbc.eduKeywords: Acyclic Nucleoside Synthesis; Ring-Expanded Acyclic Nucleoside Analogue; Biochemical Studies; Inhibition of Adenosine
Deaminase and Guanine Deaminase (Guanase)
This article was withdrawn at the end of the conference