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1.1. Porphobilinogen synthase: still a mechanistic enigma
1.3. Site selective inhibition studies
1.4. Kinetics of the inhibition studies of PBGS
1.5. Diacids as analogues of the intermediates
1.6. Inhibition studies of PBGS using diacids reported by other groups
2.1. Materials
2.2. PBGS assay and determination of kinetic constants
2.3. Estimation of the specific activity
2.4. Dialysis assay
3. Results
3.1. Inhibition of E. coli PBGS with diacids