If you are drawing a molecule from scratch, go to the BUILD menu
and select Clear from the menu items. When building a structure using
Quest, you will notice that there is no common standard for
drawing molecules on screen (unfortunately). With Quest, a click
on the screen draws the atom selected (by default C,
but in the example below
currently S). Further clicks add a further atom to the last atom. If you
want the next atom not to be added to the previous, select MOVE first. To
convert a single to a double bond, select DOUB, then MOVE and click on the bond
desired. To convert a carbon to another atom on the menu, select the type from
the screen menu and then MOVE before clicking at the desired atom. If the atom
is not present on the menu, click on OTHER. Errors can be corrected using
DELATOM or DELBND, or in extremis CLEAR which removes the entire molecule.
When you are happy with your structure, click on DEFINE STRUCTURE and then
QUEST;
At this point, you have to either KEEP or REJECT the structure before the next one is displayed. If you KEEP the structure, its co-ordinates are written to a file on disk (called penicillin.dat in this case). Continue to the end, when the exit from the database will occur. To perform a further search, type Quest <name of search> from the console window of the workstation, as shown in an earlier diagram above. At any stage you can also go to the alternative 3D projection, in which bond lengths, angles etc can be displayed on the screen.
It is not possible to easily copy any "live" structures from the screen to Claris Works. You can take a "screen snapshot" by pressing the Print Screen key (F13). Drag out a capture area, click on the camera, and then paste the resulting image to Claris.