LEUCINE:
NO REPORTED HAZARDS - TREAT AS HARMFUL
Colourless solid; m.p. 293-6ºC. Soluble in water.
Spillage & disposal:Wash areas with water.
ACETIC ACID:
FLAMMABLE
CAUSES SEVERE BURNS
Colourless liquid, with acrid pungent odour; b.p. 118ºC, m.p. 17ºC. Soluble in water. OEL 25mgm-3
Toxic effects:Causes severe burns. Causes internal irritation and damage if taken by mouth.
Irritiating vapour.
Hazardous reactions:Dangerous in contact with chromic acid, sodium peroxide, and nitric acid. Causes
vigourous exothermic polymerisation with acetaldehyde.
Spillage & disposal:Wash areas with water and then ventilate to dispel residues.
DICHLOROMETHANE:
HARMFUL BY INHALATION, INGESTION, AND SKIN CONTACT
POSSIBLE RISK OF IRREVERSIBLE EFFECTS
IRRITATING TO EYES
Colourless volatile liquid with chloroform-like odour; b.p. 40ºC; immiscible with water. Avoid breathing vapour.
Avoid contact with skin and eyes. MEL 350 mgm-3.
Toxic effects:The vapour irritates the eyes and respiratory system and may cause headaches and nausea;
high concentrations may result in cyanosis and unconsciousness. The liquid irritates the
eyes. Poisonous if taken by mouth.
Hazardous reactions:Mixtures with Li, Na, N2O4, HNO3liable to explode.
Spillage & disposal:Wear goggles, gloves, and laboratory coat. Absorb bulk quantities on sand, shovel into
buckets. Wash site of spillage with water and detergent. Dichloromethane should be
placed in chlorinated waste contyainers for central disposal
METHANOL:
HIGHLY FLAMMABLE
TOXIC BY INHALATION AND IF SWALLOWED
Colourless volatile liquid with characteristic odour; b.p. 65ºC. Misible with water in all proportions. Toxic by
ingestion. OEL 260 mgm-3
Toxic effects:Toxic by ingestion. Damaging to eyes. Vapour may cause headache and nausea.
Chronic effects: may damage central nervous system and internal organs.
Hazardous reactions:Can react vigourously with oxidising materials. Can react violently with chloroform in
contact with sodium or potassium hydroxide.
Spillage & disposal:Dilute with water and run to waste. Ventilate area to dispel residual vapour.
