I am exploring the fascinating diverse facets of a recently published laboratory experiment for undergraduate students.[cite]10.1021/acs.jchemed.7b00566[/cite] Previously I looked at a possible mechanistic route for the reaction between an enal (a conjugated aldehyde-alkene) and benzyl chloride catalysed by base and a chiral amine, followed by the use of NMR coupling constants to assign relative stereochemistries. Here I take a look at some chiroptical techniques which can be used to assign absolute stereochemistries (configurations).
Posts Tagged ‘Vibrational circular dichroism’
Organocatalytic cyclopropanation of an enal: (computational) assignment of absolute configurations.
Saturday, September 1st, 2018Multispectral Chiral Imaging with a Metalens.
Saturday, January 6th, 2018The title here is from an article on metalenses[cite]10.1021/acs.nanolett.6b01897[/cite] which caught my eye.