In an attempt to circumvent this abnormal rearrangement, (1 + 2 -> 3), we are currently investigating the Barton-Zard reaction with 7 and 8. Also, we are close to completing a synthesis of the novel 2-nitro-(phenylsulfonyl)indole (9). These three substrates should provide good leads into the important pyrrolo[3,4-b]indole ring system via the Barton-Zard reaction.
| Title |
| 2 |
| 3 |
| 4 |
| 5 |
| 6 |
| Acknowledgements |