PROPERTIES

SALBUTAMOL PHYSICAL DATA:
 
 

CAS Registry: [18559-94-9]
Systematic 
Name:
(±)alpha1-[(tert-butylamino)methyl]-4-hydroxy-m-xylene-alpha,alpha'-diol
Synonyms: Aerolin;Airet;Airomir;AlbuterolSulfate;Almotex;Anebron;Asmadil;Asmalin;
Asmanil;Asmasal;Asmatol;Asmaven;Asmidon;Asmol;AsmolUni-Dose;Asthalin;
Broncho-Spray;Broncovaleas;Bronter;Bugonol;Butamol;Buto-Asma;Butotal;
Cobutolin;Dilatamol;Farcolin;Grafalin;Libretin;Medolin;Mozal;Novosalmol;
Parasma;Proventil;Respax;Respolin;Sabutal;Sabutamol;Salbetol;Salbron;Salbulin;
Salbusian;Salbutalan;Salbutamol;Salbutan;Salbutol;Salbuven;Salbuvent;
Salmaplon;Salomol;Sedalin;Sultanol;Suprasma;Theosal;Tobybron;Vencronyl;
Venetlin;Ventilan;Ventodisks;Ventolin;Ventoline;VentolinRotacaps;Volmax
Generic 
Class:
beta2-adrenergic bronchodilator
FDA Drug 
Class:
Antiasthmatics/Broncodilators
Antihypertensives
Molecular
Formula:
C13H21NO3
Molecular 
Weight:
239.31 g/mol
Melting
Point:
157-158 oC (with decomposition) 13
Description: A white or almost white, crystalline powder.
Clear solution in methanol, very pale clear yellow solution.20
Solubility: Sparingly soluble in water; soluble in ethanol (96%); slightly soluble in ether.20
Composition: C 65.25
H 8.84
N 5.85
O 20.06
Molecular 
Structure:

   
Isomers:
R Salbutamol
           
S Salbutamol
           

 

SPECTRA:     NB Click on spectra to enlarge

IR

Salbutamol (potassium bromide disk):

Salbutamol Sulphate (potassium bromide disk):

 

NMR8:

Salbutamol H1
DMSO-d6 270 Mhz

Delta/ppm
J/Hz
Type
Integral
Assignment
1.02
-
s
9
a
2.55
9.9
d
2
b
4.42
6.6
t
1
c
4.47
-
s
2
d
4.60
-
br, D2O exchangable
4
e
6.69
7.9
d
1
f
6.99
7.9
d
1
f
7.27
-
s
1
f

Sepctrum produce with gNMR:

 

Salbutamol 13C
DMSO-d6 67.80 Mhz

Delta/ppm: 28.74, 49.78, 50.67, 58.34, 72.29, 114.02, 124.85, 125.06, 127.90, 134.51, 153.10



 
 
 
 
 

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