Peroxydisulfate – “enables a non-enzymatic Krebs cycle precursor”
The Wikipedia entry on peroxydisulfate is quite short (as of today). But I suspect this article may change things.[cite]10.1038/s41559-017-0083[/cite].
A search of the Cambridge structure database reveals around 18 high quality crystal structures containing this species are known, many as metal salts.
The article[cite]10.1038/s41559-017-0083[/cite] reports that “in the presence of sulfate radicals generated from peroxydisulfate, the (Krebs cycle) intermediates underwent 24 interconversion reactions” covering “the critical topology of the oxidative Krebs cycle, the glyoxylate shunt and the succinic-semialdehyde pathway“. The suggestion therefore is that these crucial metabolic reactions may have existed before life itself absorbed them into the oxidative Krebs cycle. The challenge now is to explain how or if the more ancient reductive Krebs cycle (which fixes carbon dioxide) might have arisen prebiotically. More exciting stuff to come I fancy.
An article with the title shown above in part recently appeared.[cite]10.1038/s41598-017-02687-z[/cite] Given the apparent similarity of HF1- to CH3F1- and CH3F2-, the latter of which I introduced on this blog previously, I thought it of interest to apply my analysis to HF1-. The authors[cite]10.1038/s41598-017-02687-z[/cite] conclude that "the F atom of HF−…
Here is another selection from the Molecules-of-the-Year shortlist published by C&E News, in which hexagonal planar transition metal coordination is identified. This was a mode of metal coordination first mooted more than 100 years ago,[cite]10.1038/s41586-019-1616-2[/cite] but with the first examples only being discovered recently. The C&E News example comprises a central…
Nowadays, data supporting most publications relating to the synthesis of organic compounds is more likely than not to be found in associated "supporting information" rather than the (often page limited) article itself. For example, this article[cite]10.1021/jacs.6b13229[/cite] has an SI which is paginated at 907; almost a mini-database in its own right!†…
