3.   Laboratory suitable method

This reaction mechanism is suitable for laboratory synthesis as it requires mild conditions and requires chemicals which are readily available to give a good yield of dlucanazole (>42%)

1. Conversion an epoxide to Fluconazole  2.   Lithiated or grignard difluorobenzene to Fluconazole
3.   Laboratory suitable method    4.   Commercially viable method: Sulphate process